		Technical Data
C1035-27Z1	CAPN3, ID (Calpain-3, Calpain L3, Calpain p94, Calcium-activated Neutral Proteinase 3, CANP 3, Muscle-specific Calcium-activated Neutral Protease 3, New Calpain 1, nCL-1, NCL1, CANPL3, CANP3)

Description:
CAPN3, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. The protein is a muscle-specific member of the calpain large subunit family that specifically binds to titin.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the Center region of human CAPN3 (KLH).

Purity:

Purified by ammonium sulfate precipitation.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human CAPN3.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Moretti,D., Del Bello,B. Carcinogenesis 30(6), 960-967 (2009). 2.Beckmann,J.S. and Spencer,M. Neuromuscul. Disord. 18(12), 913-921 (2008). 3.Kramerova,I., Kudryashova,E. Hum. Mol. Genet. 17(21), 3271-3280 (2008). 4.Sorimachi,H., Kinbara,K. J. Biol. Chem. 270(52), 31158-31162 (1995).