		Technical Data
C1077-45C	ANTXR2 (Anthrax Toxin Receptor 2, Capillary Morphogenesis Gene 2 Protein, CMG-2, CMG2)

Description:
Necessary for cellular interactions with laminin and the extracellular matrix.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:16,000
Western Blot: 0.3-1ug/ml, human, mouse and rat kidney lysates observed on ~60kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to C-HEGLKLANEQIQK, from ANTX2, at the internal regoin of the protein (NP_477520.2, NP_001139266.1).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human ANTXR2. Species Crossreactivity: Mouse and rat. Species sequence homology: Bovine and canine.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Deuquet J, Abrami L, Difeo A, Ramirez MC, Martignetti JA, van der Goot FG, Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. Human mutation 2009 Apr 30(4):583-9.