Technical Data
C1209-55
CPN1, NT (Carboxypeptidase N Catalytic Chain, CPN, Carboxypeptidase N Polypeptide 1, Carboxypeptidase N Small Subunit, Lysine Carboxypeptidase, Arginine Carboxypeptidase, Kininase-1, Serum Carboxypeptidase N, SCPN, Anaphylatoxin Inactivator, Plasma Carbox
Description:
CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the N-terminal region of human CPN1 (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human CPN1. Species Crossreactivity: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Davis,D.A., Singer,K.E. Blood 105(12), 4561-4568 (2005). 2.Riley,D.A., Tan,F. Genomics 50(1), 105-108 (1998). 3.Hendriks,D., Vingron,M. Biol. Chem. Hoppe-Seyler 374(9), 843-849 (1993).