Technical Data
C1350-41C
CARD14, CT (Caspase Recruitment Domain-containing Protein 14, CARD-containing MAGUK Protein 2, Carma 2, CARMA2)
Description:
CARD (caspase recruitment domain) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. CARD belongs to the membrane-associated guanylate kinase (MAGUK) family and activates nuclear factor-Kappa-B through BCL10. The family members show differences in tissue expression.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Human CARD14
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:
Recognizes human CARD14.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.