Technical Data
C1385-25F
CARMA1 (Bimp2, CARD11, Caspase Recruitment Domain-containing Protein 11, CARD-containing MAGUK Protein 1)
Description:
Caspase recruitment domain family member 11 (CARD11, also known as CARMA1), a member of the membrane-associated guanylate kinase-like (MAGUK) family. These proteins act as molecular scaffolds assisting in the assembly of signal transduction molecules. CARD11 phosphorylates BCL10 and induces NF-kappa-B activity via BCL10 and IKK.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 0.5-2.0ug/ml ~125kD in human thymus cell lysate
Immunohistochemistry (Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to the carboxy terminus of human CARD11.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:
Recognizes human CARMA1. Species Crossreactivity: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.