Technical Data
C2097-30
Cathepsin D (CatD, CLN10, CPSD, CTSD, Lysosomal aspartyl peptidase, MGC2311)
Description:
Fine granular cytoplasmic staining is seen in macrophages and tumor cells reflecting the lysosomal location of the protein. Thus stained cells will often be inconspicuous at low power when only a light staining effect may be seen; medium and high power reveal the lysosomal staining.

Applications:
Immunohistochemistry Typical working dilution 1:100–1:200 using standard ABC technique, 60 minutes incubation at 25 °C. Effective on paraffin-embedded and fresh frozen tissue. Trypsinisation may be required.

Positive Control: Many tissues, e.g. most breast carcinomas, have a “built-in” control in the form of tissue macrophages. Alternatively human liver can be used as a control.
TypeIsotypeCloneGrade
MabIgG2b2Q538Supernatant
SizeStorageShippingSourceHost
500ul-20°CBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Cathespin-D purified from human spleen.
Purity:
Supernatant
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Human Cathepsin-D.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cancer (1990). 65:265–271. 2. Cell (1980). 20:353–362.