Technical Data
C2099-65E
CCR1 (Chemokine Receptor 1, CC-CKR-1)
Description:
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.

Applications:
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested.

Recommended Dilution:
ELISA: 1:50,000
Western Blot: 1:1000
Immunohistochemistry (Frozen, Paraffin): 1:300
Flow Cytometry: 1:20
Optimal dilutions to be determined by the researcher.

Positive Control:
Human peripheral blood leukocytes or T-cell line Jurkatt.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ul-20°CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to aa7-24,TEDYDTTTEFDYGDATPC from human CCR1. Cellular Localization: Cell Membrane
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, sodium azide.
Specificity:
Recognizes human CCR1. Peptide sequence is < 50% identical to other human chemokine receptors in this region. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Su SB et al. J Leukoc Biol 60:658-66 (1996). 2. Neote K et al. Cell 72:415-25 (1993).