Technical Data
C2099-66C
CCR2 (Chemokine Receptor 2, CC-CCR-2, CKR2)
Description:
CCR2 is an integral membrane protein. It is receptor for the MCP-1, MCP-3 and MCP-4 chemokines. It transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Recommended Control:
Pooled pre-immune background control

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgYAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanChicken
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to aa1-45. Protein GI Number: 4502633. Protein Accession #: NP_000638.1
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity:
Recognizes human Chemokine Receptor 2, C-C motif.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Abbadie, C., et al., Proc. Nat. Acad. Sci. 100: 7947-7952 (2003).