		Technical Data
C2099-66C	CCR2 (Chemokine Receptor 2, CC-CCR-2, CKR2)

Description:
CCR2 is an integral membrane protein. It is receptor for the MCP-1, MCP-3 and MCP-4 chemokines. It transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Recommended Control:
Pooled pre-immune background control

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab	IgY		Affinity Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Chicken

Concentration:

~1mg/ml

Immunogen:

Synthetic peptide corresponding to aa1-45. Protein GI Number: 4502633. Protein Accession #: NP_000638.1

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.

Specificity:

Recognizes human Chemokine Receptor 2, C-C motif.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Abbadie, C., et al., Proc. Nat. Acad. Sci. 100: 7947-7952 (2003).