Technical Data
CCR2 (C-C Chemokine Receptor Type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, JE/FIC Receptor, MCP-1 Receptor, CD192, Cmkbr2) (APC)
CCR2 is a G-protein linked seven transmembrane domain spanning chemokine receptor that preferentially binds monocyte chemoattractant proteins-1 and -3 (MCP-1 and MCP-3). Cells that respond to the action of MCP-1 and therefore are likely to express CCR2 receptors include monocytes, T cells, NK cells, basophils, mast cells, and dendritic cells.

Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Flow Cytometry: 10ul to label 1x10e6 cells.
Optimal dilutions to be determined by the researcher.

Fusion of a mouse myeloma with B cells obtained from a rat immunized with L1.2 cells transfected with mouse CCR2.

Storage and Stability:
Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
MabIgG2B10K31Affinity Purified
100Tests4C Do Not FreezeBlue IceMouseRat
L1.2 cells transfected with mouse CCR2.
Purified by Protein G affinity chromatography.
Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Detects mouse and rat CCR2 transfectants but not the parental cell line in flow cytometry. Does not detect HEK293 human embryonic kidney cell line transfected with mouse CCR5 in Flow Cytometry.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Apuzzo T, Bachi A, Bianchi ME, Celona B, De Marchis F, Livoti E, Mellado M, Munoz LM, Pedotti M, Proudfoot A, Raucci A, Schiraldi M, Thelen M, Uguccioni M, Varani L, Venereau E J. Exp. Med. 2012 209:551-63