Technical Data
C2099-91G
CCR2 (Chemokine Receptor 2, CC-CCR-2, CKR2)
Description:
CCR2 is an integral membrane protein. It is receptor for the MCP-1, MCP-3 and MCP-4 chemokines. It transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection.

Applications:
Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunocytochemistry: 1:400
Immunohistochemistry (Paraffin sections): 1:200
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ug-20°CBlue IceHumanGoat
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide corresponding to aa17-39 (G17EEVTTFFDYDYGAPCHKFDVKQ39) of the N-terminal extracellular domain of human CCR2 (C-C chemokine receptor 2).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 1mg/ml BSA, 0.1% sodium azide.
Specificity:
Recognizes human CCR2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Charo, I.F., et al., PNAS 91: 2752 (1994).