		Technical Data
C2099-99F3	CCR5 (Chemokine (C-C motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5, CC-CKR-5, C-C CKR-5, CCR-5, AM4-7, CD195, CHEMR13, CKR5, CMKBR5, FLJ78003, HIV-1 Fusion Coreceptor, IDDM22) (PE)

Description:
CCR5 cell surface antigen is a 45kD glycoprotein also known as CD195. CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also serves as a co-receptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: Neat-1:5; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

Type	Isotype	Clone	Grade
Mab	IgG2a	3H634	Affinity Purified

Size		Storage	Shipping	Source	Host
100 Tests		4°C/-20°C (No Glycerol)	Blue Ice	Human	Rat

Concentration:

Not determined

Immunogen:

CHO cells transfected with human CCR5.

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a lyophilized powder from PBS, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.

Specificity:

Recognizes human CCR5 at ~45kD.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.