Technical Data
C2099-99K
CCR5 (Chemokine (C-C Motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5, CC-CKR-5, C-C CKR-5, CCR-5, CD195, CHEMR13, CKR5, CKR-5, CMKBR5, FLJ78003, HIV-1 Fusion Coreceptor, IDDM22)
Description:
CCR5 cell surface antigen is a 45kD glycoprotein also known as CD195. CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also serves as a co-receptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:50-1:100 10ul labels 10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2aHEK/1/85aPurified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRat
Concentration:
~0.1mg/ml
Immunogen:
CHO cells transfected with human CCR5.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human CD195 at ~45kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Mueller, A. et al. (2002). Pathways for internalization and recycling of the chemokine receptor CCR5. Blood. 99:785-791.