Technical Data
C2099-99K1
CCR5 (Chemokine (C-C Motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5, CC-CKR-5, C-C CKR-5, CCR-5, CD195, CHEMR13, CKR5, CKR-5, CMKBR5, FLJ78003, HIV-1 Fusion Coreceptor, IDDM22) (FITC)
Description:
CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin and also
serves as a co-receptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 10ul labels of a neat-1:10 working dilution to 10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG2aHEK/1/85aPurified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseRat
Concentration:
~0.1mg/ml
Immunogen:
CHO cells transfected with human CCR5.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.09% sodium azide, 1% BSA. Labeled with FITC.
Specificity:
Recognizes human CD195 at ~45kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Mueller, A. et al. (2002) Pathways for internalization and recycling of the chemokine receptor
CCR5. Blood. 99: 785-791.