Technical Data
C2099-99K2
CCR5 (Chemokine (C-C Motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5, CC-CKR-5, C-C CKR-5, CCR-5, CD195, CHEMR13, CKR5, CKR-5, CMKBR5, FLJ78003, HIV-1 Fusion Coreceptor, IDDM22) (PE)
Description:
CD195 acts as a receptor for a number of chemokines including RANTES and eotaxin
and also serves as a co-receptor for the entry of HIV into cells. CD195 is expressed by a subset of T lymphocytes and by monocytes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 10ul labels of a neat-1:5 working dilution to 10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG2aHEK/1/85aPurified
SizeStorageShippingSourceHost
100Tests4C Do Not FreezeBlue IceHumanMouse
Concentration:
Not determined.
Immunogen:
CHO cells transfected with human CCR5.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.9% sodium azide, 1% BSA. Labeled with R-Phycoerythrin (PE).
Specificity:
Recognizes human CD195 at ~45kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Mueller, A. et al. (2002) Pathways for internalization and recycling of the chemokine receptor
CCR5. Blood. 99:785-791.