Technical Data
C2100-16
CCR10 (CC Chemokine receptor 10, CC-CCR-10, G protein-coupled receptor 2, GRP2)
Description:
Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes. Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation. Chemokines act through seven transmembrane G protein-coupled receptors. The chemokine system is increasingly recognized to play an important role in lymphocyte biology.

Application(s):
ELISA: 1:100,000
Western Blotting: 1:1,000
Immunohistochemistry: 1:250

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseGoat
Concentration:
As reported
Immunogen:
Synthetic peptide KPTEQVSWGLYSGYDEEAYSVGPLPELC corresponding to aa 4-31 of mouse CCR10.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide before the addition of 40% glycerol.
Specificity:
Peptide sequence is < 50% identical to other mouse chemokine receptors in this region. Recognizes mouse CCR10 and has minimal crossreactivity to human CCR10. Crossreacts with mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Zaballos,A.,. et. al. identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK. J. Immunol. 162 (10), 5671-5675 (1999)
2. Wang, W., et al. 2000. J. Biol. Chem. 275, 22313