Technical Data
C2251-02C
CD1 (PE)
Description:
Porcine CD1 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It has a domain organization similar to that of MHC class I molecules and is expressed in association with Beta2-microglobulin. CD1 is found on B cells, macrophages and immature thymocytes. There is evidence for a role of CD1 in presentation of lipids and peptides to T cells.1-3

Applications:
Suitable for use in Flow Cytometry and Immunohistochemistry. Other aapplications not tested.

Recommended Dilution:
Flow Cytometry: 0.2ug/10e6 cells
Immunohistochemistry: Acetone fixed, frozen sections.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at 4C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG2a,k5K103Purified
SizeStorageShippingSourceHost
100ug4C Do not freezeBlue IcePorcineMouse
Concentration:
~0.1mg/ml
Immunogen:
Porcine CD1.
Purity:
Purified
Form
Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Labeled with R-Phycoerythrin (PE).
Specificity:
Recognizes porcine CD1, Mr 43-49kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Denham, S., M. Shimizu, A.T. Bianchi, et al. 1994. Vet. Immunol. Immunopathol. 43:259. 2. Saalmuller, A. 1996. Immunol. Today 17:352. 3. Pescovitz, M.D., J.K. Lunney, and D.H. Sachs. 1984. J. Immunol. 133:368.