Technical Data
C2262-34E
CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)
Description:
Fusion Partner: NSO myeloma cell line

Source: Tissue culture supernatant.

Applications:
Flow cytometry
Immunohistochemical studies of rat frozen tissue sections and paraffin embedded tissue sections following periodate-lysine paraformaldehyde fixation
Immunoprecipitation

Storage and Stability: For use within 1 month of purchase store at +4C, for long term storage aliquot antibody into small volumes and store at-20C
TypeIsotypeCloneGrade
MabIgG2a2Q913Affinity Purified
SizeStorageShippingSourceHost
500ug-20CBlue IceRatMouse
Concentration:
~0.5mg/ml
Immunogen:
Rat peritoneal macrophages
Purity:
Protein G affinity chromatography
Form
Supplied as a liquid in PBS containing 10mM sodium azide
Specificity:
Recognizes most macrophages (including resident peritoneal and activated macrophages), kupffer cells, but only about 35% of alveolar macrophages. The antibody also labels dendritic cells extensively, granulocytes and cells with the morphology of microglia in brain. The antibody precipitates three polypeptides of 150, 103 and 95kD. The antibody inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for IC3b called CR3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Robinson A.P.et al. Immunology 57:239247 (1985) 2. Barclay A.N., Immunology 42:593600 (1981) 3. Milligan C.E. et al. J Comparative Neurology 314:125- 135 (1991) 4. Whiteland J.L et al. J. Histochem. Cytochem 43:313- 320. (1995).