Description:
The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.
Applications:
Suitable for use in Flow Cytometry. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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| Type | Isotype | Clone | Grade |
|---|
| Mab | IgG1 | AT10 | Purified |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 100ug | | 4°C Do Not Freeze | Blue Ice | | Mouse |
|
| Concentration: |
| As reported |
| Immunogen: |
| Human CD32. |
| Purity: |
| Purified |
| Form |
| Supplied as a liquid in 0.09% sodium azide, 1% BSA. Labeled with Biotin. |
| Specificity: |
| Recognizes human CD32, at ~ 40kD. Species Crossreactivity: canine, monkey. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Greenman, J. et al. (1991). Characterisation of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab')2 derivative for recruitment of cytotoxic effectors. Mol. Immunol. 28:1243-1254. 2. Can den Herik-Oudjik, I.E. et al. (1994). Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes. J. Immunol. 152: 574-585. 3. Lilliehook, I. et al. (1998). Expression of adhesion and Fc gamma - receptors on canine blood eosinophils and neutophils studied by anti-human monoclonal antibodies. Vet. Immunol. Immunopathol. 61:181-193. 4. Larsson, M. et al. (1997). Human dendritic cells handling of binding, uptake and degradation of free and IgG-immune complexed dinitrophenylated human serum albumin in vitro. Immunology. 90:138-146.
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