Technical Data
C2441-97A
CD91, 85kD (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein)
Description:
A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. Can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91).

Applications:
Suitable for use in Immunofluorescence, Immunohistochemistry, Flow Cytometry and Western Blot. Other applications have not been tested.

Recommended Dilutions:
Immunohistochemistry: 1:20
Optimal dilutions to be determined by researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG15F140Affinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanMouse
Concentration:
~0.05mg/ml (after reconstitution)
Immunogen:
Human CD91
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA. Reconstitute with 1ml sterile ddH2O.
Specificity:
Recognizes the 85kD b-chain of human CD91 expressed in a restricted spectrum of cell types. Species Crossreactivity: rabbit, rat, hamster and mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Strickland et al. (1990) J Biol Chem 265:17401-17404. 2. Coukos et al (1994): Am J Pathology 144:383-392. 3. Rebeck et al (1993): Neuron 11:575-580. 4. Gonias et al (1992): Am J Pathology 141:37-42. 5. Strickland DK, Kounnas MZ, Argraves WS (1995) FASEB J 9:890-898 6. Herz J and Strickland DK (2001) J. Clin. Invest. 108:779-784.