Technical Data
C2555-01B
Cdc14A (CDC14 Cell Division Cycle 14 Homolog A, CDC14 Homolog A, Cell Division Cycle 14 Homolog A, Cdc14A1, Cdc14A2, Cdc14, Dual Specificity Protein Phosphatase CDC14A, hCDC14) (Azide Free)
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Technical Data |
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C2555-01B |
Cdc14A (CDC14 Cell Division Cycle 14 Homolog A, CDC14 Homolog A, Cell Division Cycle 14 Homolog A, Cdc14A1, Cdc14A2, Cdc14, Dual Specificity Protein Phosphatase CDC14A, hCDC14) (Azide Free) |
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Description: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. Applications: Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1000 ELISA: 1ug/ml-3ng/ml Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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