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Technical Data |
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C2560-05M |
CDC25C, NT (Cell Division Cycle 25 Homolog C, Cdc 25C, CDC 25, Dual Specificity Phosphatase Cdc25C, M-phase Inducer Phosphatase 3, MPIP3, PPP1R60) |
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Description: M-phase inducer phosphatase 3, also known as CDC25C, is a tyrosine phosphatase expressed predominantly in G2 phase. It directly dephosphorylates CDC2 and triggers entry into mitosis. M-phase inducer phosphatase 3 is also thought to suppress p53-induced growth arrest. At least 5 isoforms are produced by alternative splicing. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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