Technical Data
C2584-01
CDw17 (Lactosylceramide)
Description:
Lactosylceramide (LaCer) is present on peripheral blood granulocytes including basophils, monocytes, platelets and a subset of B cells (40-80% CD19+). In tissues, CDw17 is found on tonsillar dendritic cells, epithelial cells, intestinal epithelium and endothelial. CDw17 antigen may play a role in phagocytosis.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1ug labels 1x10e6 cells or 100ul peripheral bllod.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgM5F20Highly Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Human CDw17
Purity:
Purified by hydroxyapatite chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Recognizes human CDw17 (Lactosylceramide). Reacts with normal human platelets (49%), peripheral blood lymphocytes (11%), monocytes (16%), and granulocytes (74%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Tadamitsu K, K.Hitoshi, A.E.G.Kr. van dem Borne, et al., eds. 1997. Leukocyte Typing VI: White Cell Differentiation Antigens.P:626-628 Garland Publishing, Inc., New York.