Technical Data
C2617-02A3
ADAP1 (Arf-GAP with Dual PH Domain-containing Protein 1, Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating Protein PM25, CENTA1)
Description:
GTPase-activating protein for the ADP ribosylation factor family. Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Western Blot: 1-3ug/ml, observed in human and mouse brain lysates on ~40kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-QEYAVEAHFKHKP, from ADAP1, at C-terminal (NP_006860.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human ADAP1. Species Crossreactivity: Mouse. Species sequence homology: Canine, porcine and rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Moore CD, Thacker EE, Larimore J, Gaston D, Underwood A, Kearns B, Patterson SI, Jackson T, Chapleau C, Pozzo-Miller L, Theibert A. The neuronal Arf GAP centaurin alpha1 modulates dendritic differentiation. J Cell Sci. 2007 Aug 1;120(Pt 15):2683-93.