Technical Data
C4250-42
Chlamydia sp. LPS
Description:
LPS is a common feature of the outer envelope of gram negative bacteria, which acts as a potent endotoxin, triggering an innate immune response. Studies have shown however, that whilst the LPS of Chlamydia trachomatis does evoke an immune response, it displays only weak endotoxic activity when compared to that of other bacteria such as Salmonella Minnesota or Neisseria gonorrhoeae.

Applications:
Suitable for use in Immunofluorescence. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
NSO/U myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a10B2220Affinity Purified
SizeStorageShippingSourceHost
1mg-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Elementary bodies from C. trachomatis strain SAF2
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in TBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes a genus specific epitope within Chlamydia lipopolysaccharide (LPS).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Ingalls, R.R. et al. (1995) The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated. Infect. Immun. 63: 3125-3130.s