Technical Data
C5838-62B
Claudin 11, CT (OSP, Oligodendrocyte Specific protein, CLDN11, OSP, OTM)
Description:
The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans- membrane domains and two extracellular loops, make up tight junction strands. Claudin-11 is an oligodendrocyte-specific protein that is expressed in the tight junctions of Sertoli cells and myelin sheaths in mice.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
250ul-20CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to C-terminal of human claudin 11.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in 10mM PBS, pH 7.4, BSA, sodium azide.
Specificity:
Recognizes human CLDN11. Species sequence homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.