Technical Data
C5838-75B
Claudin 14 (CLDN14, DFNB29)
Description:
CLDN14 is a component of tight junction (TJ) strands. Defects in CLDN14 are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness (DFNB29).

Cellular Localization: Cell Membrane

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide: SATHSGYRLNDYV, representing the C-terminus of the human protein (residues 227-239), according to NP_036262; NP_652763.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.
Specificity:
Species Crossreactivity: Tested: Human. Expected to crossreact with Human, Mouse and Rat due to sequence homology.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Wilcox ER et al. Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29. Cell 104:165-72 (2001).