Technical Data
C5839-73T1
CLEC14A (C-type Lectin Domain Family 14 Member A, Epidermal Growth Factor Receptor 5, EGFR-5, C14orf27, EGFR5, UNQ236/PRO269) (PE)
Description:
CLEC14A (C-type lectin domain family 14 member A; also EGFR5) is a 51kD (predicted) member of the C-type lectin domain family of proteins. It is a type I transmembrane protein, apparently expressed in brain and about which little is known. Mature human CLEC14A is 469aa in length. It contains a 376aa extracellular region (aa22-397) and a 72aa cytoplasmic domain. The extracellular region shows one C-type lectin like domain (aa32-175) and an EGF-like region (aa245-287). Over aa2-397, human CLEC14A shares 66% and 81%aa identity with mouse and canine CLEC14A, respectively.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Absorption: 488nm

Emission: 565-605nm

Storage and Stability:
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG2B12K67Affinity Purified
SizeStorageShippingSourceHost
100 Tests4°C Do Not FreezeBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Recombinant corresponding to aa22-397 from the extracellular domain of human CLEC14A expressed in NSO cell line.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity:
Recognizes human CLEC14A.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.