Technical Data
C7500-60
COG1 (Component of Oligomeric Golgi Complex 1, CDG2G, LDLB, Conserved Oligomeric Golgi Complex Protein 1, Low Density Lipoprotein Receptor Defect B Complementing)
Description:
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:64000
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Brain (Cerebellum, Amygdala) lysates

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide with sequence C-KAKSTRNIETKAQ, from the internal region of human COG1 (NP_061184.1).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity:
Recognizes human COG1 at ~100kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Vasile E, Oka T, Ericsson M, Nakamura N, Krieger M. IntraGolgi distribution of the Conserved Oligomeric Golgi (COG) complex. Exp Cell Res. 2006 Oct 1;312(16):3132-41. PMID: 16857184