Technical Data
Complement C1q, Human (Complement Component 1, q Subcomponent)
C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s.
C1q has a molecular weight of 492.000 and is present in plasma in an average concentration of
80 g/ml. It consists of a complex of 18 polypeptide chains of three different types, A, B and C;
6 of each type. The subcomponent C1q is responsible for the binding of C1q to immuno-
complexes an membranes via the Fc portion of the immunoglobulin.

Suitable for use in ELISA, Immunoelectrophoresis and Radial Immunodiffusion. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
1ml-20CBlue IceHumanRabbit
Not determined
C1q subunit of C1 component of human complement
Supplied as a lyophilized powder. Reconstitute in 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
Recognizes the C1q subunit of C1 component of human complement. In immunoelectrophoresis and radial immunodiffusion (Ouchterlony) against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C1q protein. May also react with complexes containing C1q. Does not react with C1r, C1s or any other plasma protein component or serum. Does not crossreact with any other component of human plasma.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.