Technical Data
C7850-19A
C4BP (C4b-binding Protein alpha Chain, C4bp, Proline-rich Protein, PRP, C4BP)
Description:
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2b10-07Affinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Native human C4 binding protein.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in borate buffered saline, pH 8.4, 0.02% sodium azide.
Specificity:
Recognizes human C4BP.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.