Technical Data
C7907-04L2
C-Reactive Protein (CRP, C-Reactive Protein Pentraxin Related, MGC88244, PTX 1, PTX1)
Description:
C-reactive protein (CRP) is a calcium-binding plasma protein which is significantly up-regulated during the acute phase response. CRP has been shown to bind phosphocholine residues, apoptotic cells and constituents of micro-organisms, and can lead to activation of leukocytes and the complement system, and the clearance of apoptotic cells.
CRP is produced in the liver in response to interleukin-1 (IL-1) and IL-6 secretion, and has a monomer molar mass of 25kDa, and native cyclic pentamer mass of 125kDa.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry: frozen sections
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
1ml-20CBlue IceHumanSheep
Concentration:
~2.5mg/ml
Immunogen:
Native C-Reactive Protein from human serum
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4. Preservative free.
Specificity:
Recognizes human C-Reactive Protein.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. de Ferranti, S.D. and Rifai, N. (2007) C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc. Pathol. 16: 14-21. 2. de Ferranti, S.D. and Rifai, N. (2007) C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc. Pathol. 16: 14-21 3. Yeh, E.T. (2004) CRP as a mediator of disease. Circulation. 109(21 Suppl 1):II11-4. 4. Yeh, E.T. (2004) CRP as a mediator of disease. Circulation. 109(21 Suppl 1):II11-4.