Technical Data
CRYAB (Alpha-crystallin B Chain, Alpha(B)-crystallin, Heat Shock Protein beta-5, HspB5, Renal Carcinoma Antigen NY-REN-27, Rosenthal Fiber Component, CRYA2)
a-b-Crystalline is a lens protein, which has some homology with the small heat shock proteins. It is expressed in tissues such as skeletal muscle, cardiac muscle, smooth muscle, renal tubular epithelium, Schwanncells, glial cells, thyroid epithelium, colonic epithelium and stratified squamous epithelium. This antibody may be useful in the identification of Lewy body dementia.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.01-0.03ug/ml, observed in human skeletal muscle and mouse eye lysates on ~18-19kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
100ug-20CBlue IceHumanGoat
Synthetic peptide corresponding to C-RLEKDRFSVNLD, from CRYAB, at the internal region of the protein (NP_001876.1).
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Recognizes human CRYAB. Species Crossreactivity: Mouse. Species sequence homology: Rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.