Technical Data
C7944-60G
CRYAB (Alpha-crystallin B Chain, Alpha(B)-crystallin, Heat Shock Protein beta-5, HspB5, Renal Carcinoma Antigen NY-REN-27, Rosenthal Fiber Component, CRYA2)
Description:
a-b-Crystalline is a lens protein, which has some homology with the small heat shock proteins. It is expressed in tissues such as skeletal muscle, cardiac muscle, smooth muscle, renal tubular epithelium, Schwanncells, glial cells, thyroid epithelium, colonic epithelium and stratified squamous epithelium. This antibody may be useful in the identification of Lewy body dementia.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.01-0.03ug/ml, observed in human skeletal muscle and mouse eye lysates on ~18-19kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-RLEKDRFSVNLD, from CRYAB, at the internal region of the protein (NP_001876.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human CRYAB. Species Crossreactivity: Mouse. Species sequence homology: Rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.