Cellular Localization: Nuclear
Positive Control: Tonsil
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry (Fr) (paraffin-embedded sections). Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
| Not determined|
|Synthetic peptide (Human).|
|Supplied as a liquid in PBS, pH 7.2.|
|This antibody reacts with a 76kDa protein, known as Cullin 2. Species Crossreactivity: Crossreacts with Human and Mouse. |
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
Michel JJ & Xiong Y Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A. Cell Growth Differ 9:435-49 (1998). <9663463>Kipreos ET et al. cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family. Cell 85:829-39 (1996). <8681378>|