Technical Data
C7949-20C
Cullin 3 (CUL-3)
Description:
Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene. Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.

Applications:
Suitable for use in Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Immunoprecipitation: 2-5ug/mg
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug4C (-20C Glycerol)Blue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
An epitope that maps to a region between residue 225 and 275 of human cullin 3.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
Specificity:
Recognizes human Cullin 3.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.