		Technical Data
C7949-20C	Cullin 3 (CUL-3)

Description:
Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene. Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.

Applications:
Suitable for use in Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Immunoprecipitation: 2-5ug/mg
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		4°C (-20°C Glycerol)	Blue Ice	Human	Rabbit

Concentration:

~1mg/ml

Immunogen:

An epitope that maps to a region between residue 225 and 275 of human cullin 3.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.

Specificity:

Recognizes human Cullin 3.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.