		Technical Data
C7949-20D	Cullin 3 (CUL-3)

Description:
Cullin 3 is a member of the family of human Cullin genes (CUL-1, -2, -3, -4a, -4b and -5) homologous to the S. cerevisiae cdc53 gene.

Cullin 3 forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by proteosomes.

Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.2mg/ml

Immunogen:

Antibody was affinity purified using an epitope specific to Cul3 immobilized on solid support.The epitope recognized by this antibody maps to a region between residue 650 and 700 of human cullin 3 using the numbering given in entry NP_003581.1 (GeneID 845

Purity:

Purified by immunoaffinity chromatography.

Form

Tris-buffered Saline 0.1% BSA

Specificity:

Species Crossreactivity: Human and Mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.