Technical Data
C7949-21N1
Cullin 5 (CUL-5)
Description:
Cullins (1, 2, 3, 4a, 5 and 7) are a family of proteins that assemble a large number of ubiquitin ligases to catalyse polyubiquitiation, as well as binding to various specific factors to recruit substrates. Cullin 5 (CUL 5) is a component of E3 ubiquitin ligase complexes and it is involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kD protein. It may also form a cell surface vasopresin receptor and it may play a role in brast tumorigenesis.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:2000-1:10,000
Western Blot: 1:500-1:1,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabSerum
SizeStorageShippingSourceHost
100ul-20CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide, SNLLKNKGSLQFEDK, corresponding to aa4-18 of human Cul5, N-terminus (KLH).
Purity:
Purified by delipidation and defibrination.
Form
Supplied as a liquid, 0.01% sodium azide.
Specificity:
Recognizes human Cullin 5 at ~90.9kD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.