Technical Data
C8452-08E
Cyclin A
Description:
This antibody may be used to examine the biological behavior of tumors. Cyclins are proteins that vary in abundance and are associated with and activate cyclin dependent kinases at different stages of the cell cycle. Cyclin A is detectable in S phase increasing during progression into G2 phase. Increased expression of various cyclins have been noted in some human cancers.

Cellular Localization: Nuclear

Positive Control: Tonsil

Applications:
Suitable for use in Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG1,k8J1103Supernatant
SizeStorageShippingSourceHost
500ul-20CBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Synthetic peptide to the N-terminus of Cyclin A protein (Human).
Purity:
Tissue culture supernatant
Form
As reported
Specificity:
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
i) Bodey et al. Modern Pathol 7: 846, 1994.
ii) Inohara et al. Arch Dermatol Res 286: 504, 1994.
iii) Dutta et al. Natl Acad Sci 92: 5386, 1995