Technical Data
C8855-61A
Cyclophilin F, aa30-207, Recombinant, Human (Peptidyl Prolyl Cis Trans Isomerase F, PPIASE)
100ug
Molecular Biology Storage: -20CShipping: Blue Ice
Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-trans isomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

Sequence of amino acids:
MGSSHHHHHH SSGLVPRGSH CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS
KSGRTSKKIV ITDCGQLS

Molecular Weight: 21kD (198aa)

Endotoxin: 1.0 EU/ug of protein (determined by LAL method)

Storage and Stability:
For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
21kD
Source: E. coli
Purity: 95% by SDS PAGE. Recombinant, Human PPIF protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris pH 7.5, 1mM DTT, 10% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Bergsma DJ., et al. (1991) J Biol Chem. 266(34):23204-14. 2. Bowles KR., et al. (2000) Genomics 67(2):109-27.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.