Technical Data
C8929-03H1
CYP26B1 (Cytochrome P450 26B1, Cytochrome P450 26A2, Cytochrome P450 Retinoic Acid-inactivating 2, Cytochrome P450RAI-2, Retinoic Acid-metabolizing Cytochrome, CYP26A2, P450RAI2)
Description:
CYP26B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:3000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
50ul-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Recombinant corresponding to aa160-396 from human Cytochrome P450 26B.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in 0.1M Tris-glycine, pH 7, 0.01% thimerosal, 20% glycerol.
Specificity:
Recognizes human CYP26B1. Species sequence homology: mouse (94%) and rat (94%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.