		Technical Data
C9095-19L	CYP11A1, NT (Cholesterol Side-chain Cleavage Enzyme, Mitochondrial, CYPXIA1, Cytochrome P450 11A1, CYPXIA1, Cytochrome P450(scc), Cholesterol Desmolase, CYP11A)

Description:
CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
200ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the N-terminal region of human CYP11A1 (KLH).

Purity:

Purified by ammonium sulfate precipitation.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human CYP11A1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Celhar,T., Cancer Genet. Cytogenet. 187(1), 28-33 (2008). 2.Morales,A., Pancreas 37(2), 165-169 (2008). 3.Shigematsu,K., Eur. J. Endocrinol. 158(6), 867-878 (2008).