		Technical Data
C9095-29H	CYP26A1, ID (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1, Cytochrome P450, 26A1, Retinoic Acid-metabolizing Cytochrome, Cytochrome P450 Retinoic Acid-Inactivating 1, Cytochrome P450RAI, hP450RAI, Retinoic Acid 4-hydroxylase, CYP26, P450RAI1)

Description:
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H+ currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to Internal region of human CYP26A1 conjugated to KLH.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Specificity:

Recognizes human CYP26A1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.