Technical Data
C9097-17A
Cytokeratin 17
Description:
Cytokeratin 17 is an excellent marker to distinguish myoepithelial cells from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of (mammary gland tumors). In the epidermis supratbasal stainging is found only in cornifying regions and in the outer root sheath of hair follicles.

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:5000-1:10,000 (ECL)
Immunohistochemistry (Frozen): 1:100-1:200; Incubate for 1 hour at RT.
Immunohistochemistry (Paraffin embedded): 1:50; Incubate for > 1 hour at RT.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanGuinea pig
Concentration:
Not Determined
Immunogen:
Recombinant human cytokeratin 17.
Purity:
Serum
Form
Supplied as a liquid, 0.5% BSA, 0.09% sodium azide.
Specificity:
Recognizes acidic human Cytokeratin 17 (Mr 46kD).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Demirkesen C, Hoede N, Moll R. J Cutan Pathol 22: 518-535 (1995). 2. Moll R. et al.: Differenzierungsmarker bei gynäkologischen Tumoren: Methodische und diagnostische Aspekte. In: Aktuelle Aspekte der Tumorimmunologie in der Gynäkologie. W. Zuckschwerdt Verlag (1995). 3. Jennemann R, Sandhoff R, Langbein L, Kaden S, Rothermel U, Gallala H, Sandhoff K, Wieganddt H, Grone H-J. J Biol Chem 282, 3083-3094 (2007).