Description:
Fusion Partners: Spleen cells from immunized Balb/c mice were fused with cells of the NSI mouse myeloma cell line.
Applications:
Immunohistochemistry (frozen)
Optimal working dilutions to be determined by researcher.
|
| Type | Isotype | Clone | Grade |
|---|
| Mab | IgM | 3H2075 | Affinity Purified |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 200ug | | -20°C | Blue Ice | Human | Mouse |
|
| Concentration: |
| ~0.5mg/ml |
| Immunogen: |
|
| Purity: |
| Purified by affinity chromatography. |
| Form |
| Purified IgM- liquid with 0.1% sodium azide. |
| Specificity: |
| Recognizes an epitope within the class II MHC complex. In normal tissue identifies dendritic cells and a proportion of B lymphocytes. Within the macrophage/dendritic cell populations the epitope seen by 3H2075 is co-expressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation. It will not bind to monocytes or any cells within the granulocyte series. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Poulter, L. W. et al. (1986). Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand. J. Immunol. 24: 351 - 357.
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