		Technical Data
D3520-01S	Dicer (Endoribonuclease Dicer, Helicase with RNase Motif, Helicase MOI, DICER1, HERNA, KIAA0928)

Description:
Dicer is an RNase III-like enzyme which cleaves double-stranded RNA into 21-23 nt RNAs. These RNAs are referred to as siRNA (short interfering RNA). It is believed to be essential in siRNA-mediated gene suppression.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75-7.5ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to QDKSNTDKWEKDEMTKDC from aa1389-1406 of human DICER1 (NP_085124.2).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Specificity:

Recognizes human DICER1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.