Technical Data
D3790-01J
DJ-1, CT (DJ1, Protein DJ-1, Oncogene DJ1, FLJ27376, FLJ34360, FLJ92274, Parkinson Disease Autosomal Recessive Early Onset 7, Parkinson Disease Protein 7, PARK7)
Description:
DJ-1, otherwise known as PARK7 (Parkinson disease protein 7), a member of the peptidase C56 family, highly expressed in skeletal muscle, heart, pancreas, liver, kidney and testis, which plays a role in transcriptional regulation and reaction to anti-oxidative stress.
DJ-1 exhibits cell-growth promoting and transforming activity, and protects neurons against oxidative stress and cell death. Defects in PARK7 are responsible for the autosomal recessive disorder early onset Parkinson disease 7.

Applications:
Suitable for use in ELISA and Western Blot. Other applications have not been tested.

Recommended Dilutions:
ELISA: 1:32,000
Western Blot: 0.5-1ug/ml detects a band of ~20kD in Jurkat cell lysates.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-AAQVKAPLVLKD from the C-terminal region of human DJ-1 (NP_001116849.1; NP_009193.2).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in Tris, pH 7.3, 0.05% BSA, 0.02% sodium azide.
Specificity:
Recognizes an epitope within the C-terminal (CT) region of human DJ-1. Species sequence homology: mouse, rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.