Technical Data
D3790-01J
DJ-1, CT (DJ1, Protein DJ-1, Oncogene DJ1, FLJ27376, FLJ34360, FLJ92274, Parkinson Disease Autosomal Recessive Early Onset 7, Parkinson Disease Protein 7, PARK7)
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Technical Data |
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D3790-01J |
DJ-1, CT (DJ1, Protein DJ-1, Oncogene DJ1, FLJ27376, FLJ34360, FLJ92274, Parkinson Disease Autosomal Recessive Early Onset 7, Parkinson Disease Protein 7, PARK7) |
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Description: DJ-1, otherwise known as PARK7 (Parkinson disease protein 7), a member of the peptidase C56 family, highly expressed in skeletal muscle, heart, pancreas, liver, kidney and testis, which plays a role in transcriptional regulation and reaction to anti-oxidative stress. DJ-1 exhibits cell-growth promoting and transforming activity, and protects neurons against oxidative stress and cell death. Defects in PARK7 are responsible for the autosomal recessive disorder early onset Parkinson disease 7. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: ELISA: 1:32,000 Western Blot: 0.5-1ug/ml detects a band of ~20kD in Jurkat cell lysates. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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