Technical Data
D8065-32P
DPP10 (Dipeptidyl Peptidase IV-related Protein 3, DPRP-3, Dipeptidyl Peptidase-like Protein 2, DPL2, Dipeptidyl Peptidase X, DPP X, Inactive Dipeptidyl Peptidase 10, DPRP3, KIAA1492)
Description:
DPP10 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml, observed in human bone marrow lysates on ~90kD bands
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-DEGHNVSEKSKYHL, from human DPP10, at the internal region of the protein (NP_065919.2, NP_001004360.2).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human DPP10. Species sequence homology: Bovine and canine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Malerba G, Pignatti PF. A review of asthma genetics: gene expression studies and recent candidates. J Appl Genet. 2005;46(1):93-104.