		Technical Data
D9642-01	DSS1, NT (26S Proteasome Complex Subunit DSS1, Split Hand/Foot Malformation Type 1 Protein, Deleted In Split Hand/Split Foot Protein 1, Split Hand/Foot Deleted Protein 1, SHFM1, SHFDG1)

Description:
The gene for DSS1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. DSS1 has been proposed to be a candidate for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the N-terminal region of human DSS1 (KLH).

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human DSS1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Yang, H., et al., Science 297(5588):1837-1848 (2002). 2.Marston, N.J., et al., Mol. Cell. Biol. 19(7):4633-4642 (1999). 3.Jantti, J., et al., Proc. Natl. Acad. Sci. USA 96(3):909-914 (1999). 4.Crackower, M.A., et al., Hum. Mol. Genet. 5(5):571-579 (1996). 5.Roberts, S.H., et al., J. Med. Genet. 28(7):479-481 (1991).