Technical Data
D9642-01
DSS1, NT (26S Proteasome Complex Subunit DSS1, Split Hand/Foot Malformation Type 1 Protein, Deleted In Split Hand/Split Foot Protein 1, Split Hand/Foot Deleted Protein 1, SHFM1, SHFDG1)
Description:
The gene for DSS1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. DSS1 has been proposed to be a candidate for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the N-terminal region of human DSS1 (KLH).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human DSS1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Yang, H., et al., Science 297(5588):1837-1848 (2002). 2.Marston, N.J., et al., Mol. Cell. Biol. 19(7):4633-4642 (1999). 3.Jantti, J., et al., Proc. Natl. Acad. Sci. USA 96(3):909-914 (1999). 4.Crackower, M.A., et al., Hum. Mol. Genet. 5(5):571-579 (1996). 5.Roberts, S.H., et al., J. Med. Genet. 28(7):479-481 (1991).