Technical Data
D9642-01B
DSS1 (Deleted in Split-Hand/Split-Foot 1 Region, Split Hand/Foot Malformation Type 1, SHFD1, ECD, SEM1, SHSF1, Shfdg1)
Description:
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.

Applications:
Suitable for use in ELISA. Other applications have not been tested.

Recommended Dilutions:
Peptide ELISA Titer: 1:32,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-RAELEKHGYKMETS, from the C Terminus of human SHFM1 (NP_006295.1).
Purity:
Purified by peptide affinity chromatography.
Form
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity:
Recognizes SHFM1. Species sequence homology: human, mouse, bovine, porcine.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Wei SJ, Trempus CS, Cannon RE, Bortner CD, Tennant RW. Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis.J Biol Chem. 2003 Jan 17;278(3):1758-68.