		Technical Data
E2249-79R	Elongator Complex Protein 1 (ELP1, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells Kinase Complex-associated Protein, IkappaB Kinase Complex-associated Protein, IKK Complex-associated Protein, IKBKAP, IKAP, DKFZP781H1425, DYS, FD, FLJ12497,

Description:
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq]

Applications:
Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:1,000
Immunohistochemistry (paraffin): 1.5ug/ml
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG1	11C284	Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Mouse

Concentration:

As reported

Immunogen:

Recombinant protein corresponding to a portion of amino acids within aa1242-1332 of human IKBKAP.

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).

Specificity:

Recognizes human IKBKAP.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.