		Technical Data
E2286-14	Endogenous Retrovirus Type K, Human, Envelope Protein (HERV K)

Description:
Endogenous retroviruses contribute to the evolution of the host genome and can be associated with diseases in their hosts. Human endogenous retrovirus K (HERV-K) is related to mouse mammary tumor virus (MMTV) and is present in the genomes of catarrhines (humans, apes, and cercopithecoids (old world monkeys)). All humans have about 30 to 50 HERV-K proviruses in their germline DNA. Expression of HERV-K genes has been reported in several tissues including male germ cell tumors and normal placenta where budding viral particles can be detected.

Applications:
Suitable for use in ELISA. Other applications have not been tested.

Recommended Dilutions:
ELISA: 1:2000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Mab	IgG2a	5i74	Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice		Mouse

Concentration:

~1mg/ml

Immunogen:

HERV K envelope antigen (42.8kD).

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a liquid in PBS, pH 7.4.

Specificity:

Recognizes Endogenous Retrovirus Type K, Human, Envelope Protein (HERV K).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Toenjes, R.R., et al., Virology 233: 280-291 (1997). 2. Barbulescu, M., et al., Curr. Biol. 9: 861-868 (1999).